Ministers want professional scientists, mathematicians, information technology experts and engineers to help fill the skills gaps in classrooms.
Many of England's science teachers have not studied science to degree level.
A new programme linking the teacher training agency with employers hopes to ease the way for science experts planning teaching as a second career.
Schools Minister Jim Knight said: "Britain is a world leader in science and engineering - from traditional lab coats to Grand Prix racing and computer games designers.
"We now need this 'best of British' to get into our schools and colleges and bring on the next generation.
"We need companies to encourage career switchers to take the leap and go into teaching.
"These people can help bring science alive for kids who are in school today - and ensure that more of them decide to take up science as a career. In the long term it can only benefit the UK."
